Fold-change detection in biological systems
نویسندگان
چکیده
منابع مشابه
Fold-change detection in biological systems
Many sensory systems in cells and organisms share a recurring property called fold-change detection (FCD). FCD describes a system whose dynamics – including amplitude and response time – are determined only by the relative change in input signal, rather than its absolute change. FCD entails two important features – exact adaptation and the Weber–Fechner law. Systems with FCD include bacterial a...
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Biological organisms use their sensory systems to detect changes in their environment. The ability of sensory systems to adapt to static inputs allows wide dynamic range as well as sensitivity to input changes including fold-change detection, a response that depends only on fold changes in input, and not on absolute changes. This input scale invariance underlies an important strategy for search...
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ژورنال
عنوان ژورنال: Current Opinion in Systems Biology
سال: 2018
ISSN: 2452-3100
DOI: 10.1016/j.coisb.2017.12.005